SPINAL ANAESTHESIA SUCCESS: AN OBSERVATIONAL STUDY ASSESSING SUBJECTIVE SENSATIONS DURING SPINAL ANAESTHETIC DRUG INJECTION

Spinal Anaesthesia Success: An Observational Study Assessing Subjective Sensations During Spinal Anaesthetic Drug Injection

Introduction: Spinal Anaesthesia (SA) has stood as the most favoured and dependable technique in regional anaesthesia for the past century.However, despite its widespread use, there are instances of occasional SA failure.Currently, there is no straightforward, cost-effective, and easily administered real-time test-aside from the positive aspiration

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PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Summary: The RET proto-oncogene encodes receptor tyrosine kinase, expressed primarily in tissues of neural crest origin.De-regulation of RET signaling is implicated in several human cancers.Recent phosphatome interactome analysis identified PTPRA interacting with the neurotrophic factor (GDNF)-dependent Intermediate RET-Ras-MAPK signaling-axis.Here

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Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines

Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies and a major cause of cancer related death worldwide, especially in China.Cell lines are widely used disease models for basic medical research, however, well characterized ESCC cell models from China were seldom reported.Misidentifying and cross-c

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